Forewarning Postprandial Hyperglycemia with Interpretations using Machine Learning

Abstract

Postprandial hyperglycemia (PPHG) is detrimental to health and increases risk of cardiovascular diseases, reduced eyesight, and life-threatening conditions like cancer. Detecting PPHG events before they occur can potentially help with providing early interventions. Prior research suggests that PPHG events can be predicted based on information about diet. However, such computational approaches (1) are data hungry requiring significant amounts of data for algorithm training; and (2) work as a black-box and lack interpretability, thus limiting the adoption of these technologies for use in clinical interventions. Motivated by these shortcomings, we propose, DietNudge, a machine learning based framework that integrates multi-modal data about diet, insulin, and blood glucose to predict PPHG events before they occur. Using data from patients with diabetes, we demonstrate that our model can predict PPHG events with up to 90% classification accuracy and an average F1 score of 0.93. The proposed decision-tree-based approach also identifies modifiable factors that contribute to an impending PPHG event while providing personalized thresholds to prevent such events. Our results suggest that we can develop simply, yet effective, computational algorithms that can be used as preventative mechanisms for diabetes and obesity management.

Publication
IEEE International Conference on Wearable and Implantable Body Sensor Networks (BSN’22)
Asiful Arefeen
Asiful Arefeen
Graduate Research Assistant

I am a PhD student at Arizona State University (ASU). I am working under the supervision of Professor Hassan Ghasemzadeh at the Embedded Machine Intelligence Lab (EMIL). My research topics include machine learning, health monitoring system development and mobile health. I received my B.S. in Electrical and Electronic Engineering from Bangladesh University of Engineering & Technology (BUET) in 2019.

Hassan Ghasemzadeh
Hassan Ghasemzadeh
Director

Hassan Ghasemzadeh is an Associate Professor of Biomedical Informatics at Arizona State University (ASU) and a Computer Science Adjunct Faculty at Washington State University (WSU).