Enhancing Early Detection of Cognitive Decline in the Elderly

Abstract

This presentation explores the effectiveness of large language models (LLMs) like GPT-4 and Llama 2 in identifying early signs of cognitive decline from real-world electronic health record (EHR) clinical notes. The study compares these LLMs with traditional machine learning models and introduces an ensemble method that combines their predictions. Results show that while LLMs provide complementary value, the ensemble approach significantly improves diagnostic accuracy, achieving an F1 score of 92.1% with 90.2% precision and 94.2% recall. This talk highlights how combining general-purpose LLMs with local models can support early detection of dementia-related disorders and enhance clinical decision-making.

Date
Feb 19, 2025 12:00 PM — 12:30 PM
Location
Arizona State University
Pegah Khorasani
Pegah Khorasani
Graduate Research Associate

As a doctoral candidate at Arizona State University (ASU), I am currently conducting research under the guidance of Professor Hassan Ghasemzadeh at the Embedded Machine Intelligence Lab (EMIL). My research interests encompass a range of topics, including machine learning, health monitoring system development, and mobile health.